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olig2 cre  (Jackson Laboratory)

 
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    Jackson Laboratory olig2 cre
    Late onset hypomyelination in <t>Olig2</t> ; Piga mutant brains (A) Percent genotype ratios of wildtype, Olig2 Cre/wt ; Piga flox/X female and Olig2 Cre/wt ; Piga flox/Y male survival to P21 ( n = 96, Chi-square p = 0.609). Immunostaining of MBP (B–D), CONTACTIN1 (E–G), SOX10 (H–J) and PDGFRα (K–M) in wild type (B, E, H, and K) Olig2 Cre/wt ; Piga flox/X female (C, F, I, and L) and Olig2 Cre/wt ; Piga flox/Y male (D, G, J, and M) animals. MBP and CONTACTIN1 data are from P96 (scale bar, 500 μm) while SOX10 and PDGFRα are from P21 (scale bar, 25 μm) ( n = 4 animals per genotype). Quantification of SOX10 (N, n = 3 animals per genotype, ANOVA p = 0.170), PGDFRα (O, n = 4, ANOVA p = 0.564) positive cells and the PDGFRα/SOX10 ratio (P, n = 3, ANOVA p = 0.430). Data represent individual values and the mean ± s.e.m. White arrows indicate SOX10 and PDGFRα positive cells.
    Olig2 Cre, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/olig2+cre/pmc13273472-286-4-5?v=Jackson+Laboratory
    Average 86 stars, based on 1 article reviews
    olig2 cre - by Bioz Stars, 2026-08
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    1) Product Images from "Genetic dissection of the role of Piga and Pgap2 in the embryonic mouse brain"

    Article Title: Genetic dissection of the role of Piga and Pgap2 in the embryonic mouse brain

    Journal: iScience

    doi: 10.1016/j.isci.2026.116299

    Late onset hypomyelination in Olig2 ; Piga mutant brains (A) Percent genotype ratios of wildtype, Olig2 Cre/wt ; Piga flox/X female and Olig2 Cre/wt ; Piga flox/Y male survival to P21 ( n = 96, Chi-square p = 0.609). Immunostaining of MBP (B–D), CONTACTIN1 (E–G), SOX10 (H–J) and PDGFRα (K–M) in wild type (B, E, H, and K) Olig2 Cre/wt ; Piga flox/X female (C, F, I, and L) and Olig2 Cre/wt ; Piga flox/Y male (D, G, J, and M) animals. MBP and CONTACTIN1 data are from P96 (scale bar, 500 μm) while SOX10 and PDGFRα are from P21 (scale bar, 25 μm) ( n = 4 animals per genotype). Quantification of SOX10 (N, n = 3 animals per genotype, ANOVA p = 0.170), PGDFRα (O, n = 4, ANOVA p = 0.564) positive cells and the PDGFRα/SOX10 ratio (P, n = 3, ANOVA p = 0.430). Data represent individual values and the mean ± s.e.m. White arrows indicate SOX10 and PDGFRα positive cells.
    Figure Legend Snippet: Late onset hypomyelination in Olig2 ; Piga mutant brains (A) Percent genotype ratios of wildtype, Olig2 Cre/wt ; Piga flox/X female and Olig2 Cre/wt ; Piga flox/Y male survival to P21 ( n = 96, Chi-square p = 0.609). Immunostaining of MBP (B–D), CONTACTIN1 (E–G), SOX10 (H–J) and PDGFRα (K–M) in wild type (B, E, H, and K) Olig2 Cre/wt ; Piga flox/X female (C, F, I, and L) and Olig2 Cre/wt ; Piga flox/Y male (D, G, J, and M) animals. MBP and CONTACTIN1 data are from P96 (scale bar, 500 μm) while SOX10 and PDGFRα are from P21 (scale bar, 25 μm) ( n = 4 animals per genotype). Quantification of SOX10 (N, n = 3 animals per genotype, ANOVA p = 0.170), PGDFRα (O, n = 4, ANOVA p = 0.564) positive cells and the PDGFRα/SOX10 ratio (P, n = 3, ANOVA p = 0.430). Data represent individual values and the mean ± s.e.m. White arrows indicate SOX10 and PDGFRα positive cells.

    Techniques Used: Mutagenesis, Immunostaining



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    Image Search Results


    Late onset hypomyelination in Olig2 ; Piga mutant brains (A) Percent genotype ratios of wildtype, Olig2 Cre/wt ; Piga flox/X female and Olig2 Cre/wt ; Piga flox/Y male survival to P21 ( n = 96, Chi-square p = 0.609). Immunostaining of MBP (B–D), CONTACTIN1 (E–G), SOX10 (H–J) and PDGFRα (K–M) in wild type (B, E, H, and K) Olig2 Cre/wt ; Piga flox/X female (C, F, I, and L) and Olig2 Cre/wt ; Piga flox/Y male (D, G, J, and M) animals. MBP and CONTACTIN1 data are from P96 (scale bar, 500 μm) while SOX10 and PDGFRα are from P21 (scale bar, 25 μm) ( n = 4 animals per genotype). Quantification of SOX10 (N, n = 3 animals per genotype, ANOVA p = 0.170), PGDFRα (O, n = 4, ANOVA p = 0.564) positive cells and the PDGFRα/SOX10 ratio (P, n = 3, ANOVA p = 0.430). Data represent individual values and the mean ± s.e.m. White arrows indicate SOX10 and PDGFRα positive cells.

    Journal: iScience

    Article Title: Genetic dissection of the role of Piga and Pgap2 in the embryonic mouse brain

    doi: 10.1016/j.isci.2026.116299

    Figure Lengend Snippet: Late onset hypomyelination in Olig2 ; Piga mutant brains (A) Percent genotype ratios of wildtype, Olig2 Cre/wt ; Piga flox/X female and Olig2 Cre/wt ; Piga flox/Y male survival to P21 ( n = 96, Chi-square p = 0.609). Immunostaining of MBP (B–D), CONTACTIN1 (E–G), SOX10 (H–J) and PDGFRα (K–M) in wild type (B, E, H, and K) Olig2 Cre/wt ; Piga flox/X female (C, F, I, and L) and Olig2 Cre/wt ; Piga flox/Y male (D, G, J, and M) animals. MBP and CONTACTIN1 data are from P96 (scale bar, 500 μm) while SOX10 and PDGFRα are from P21 (scale bar, 25 μm) ( n = 4 animals per genotype). Quantification of SOX10 (N, n = 3 animals per genotype, ANOVA p = 0.170), PGDFRα (O, n = 4, ANOVA p = 0.564) positive cells and the PDGFRα/SOX10 ratio (P, n = 3, ANOVA p = 0.430). Data represent individual values and the mean ± s.e.m. White arrows indicate SOX10 and PDGFRα positive cells.

    Article Snippet: B6.129- Olig2 tm1.1(cre)Wdr/J or Olig2-Cre (IMSR_JAX:025567, B6.129S2- Emx1 tm1(cre)Krj/J ( Emx1-Cre , IMSR_JAX:#005628 animals were genotyped using Jackson Lab’s recommended general Cre genotyping.

    Techniques: Mutagenesis, Immunostaining

    Late onset hypomyelination in Olig2 ; Piga mutant brains (A) Percent genotype ratios of wildtype, Olig2 Cre/wt ; Piga flox/X female and Olig2 Cre/wt ; Piga flox/Y male survival to P21 ( n = 96, Chi-square p = 0.609). Immunostaining of MBP (B–D), CONTACTIN1 (E–G), SOX10 (H–J) and PDGFRα (K–M) in wild type (B, E, H, and K) Olig2 Cre/wt ; Piga flox/X female (C, F, I, and L) and Olig2 Cre/wt ; Piga flox/Y male (D, G, J, and M) animals. MBP and CONTACTIN1 data are from P96 (scale bar, 500 μm) while SOX10 and PDGFRα are from P21 (scale bar, 25 μm) ( n = 4 animals per genotype). Quantification of SOX10 (N, n = 3 animals per genotype, ANOVA p = 0.170), PGDFRα (O, n = 4, ANOVA p = 0.564) positive cells and the PDGFRα/SOX10 ratio (P, n = 3, ANOVA p = 0.430). Data represent individual values and the mean ± s.e.m. White arrows indicate SOX10 and PDGFRα positive cells.

    Journal: iScience

    Article Title: Genetic dissection of the role of Piga and Pgap2 in the embryonic mouse brain

    doi: 10.1016/j.isci.2026.116299

    Figure Lengend Snippet: Late onset hypomyelination in Olig2 ; Piga mutant brains (A) Percent genotype ratios of wildtype, Olig2 Cre/wt ; Piga flox/X female and Olig2 Cre/wt ; Piga flox/Y male survival to P21 ( n = 96, Chi-square p = 0.609). Immunostaining of MBP (B–D), CONTACTIN1 (E–G), SOX10 (H–J) and PDGFRα (K–M) in wild type (B, E, H, and K) Olig2 Cre/wt ; Piga flox/X female (C, F, I, and L) and Olig2 Cre/wt ; Piga flox/Y male (D, G, J, and M) animals. MBP and CONTACTIN1 data are from P96 (scale bar, 500 μm) while SOX10 and PDGFRα are from P21 (scale bar, 25 μm) ( n = 4 animals per genotype). Quantification of SOX10 (N, n = 3 animals per genotype, ANOVA p = 0.170), PGDFRα (O, n = 4, ANOVA p = 0.564) positive cells and the PDGFRα/SOX10 ratio (P, n = 3, ANOVA p = 0.430). Data represent individual values and the mean ± s.e.m. White arrows indicate SOX10 and PDGFRα positive cells.

    Article Snippet: Mouse: Olig2 -Cre; B6.129- Olig2 tm1.1(cre)Wdr /J , The Jackson Laboratory , RRID:IMSR_JAX:025567.

    Techniques: Mutagenesis, Immunostaining